Suggested criteria for the diagnosis: (Either 2 major or 1 major + 2 minor)
Major
- Exposure for external stimulus (infection, vaccine, silicone, adjuvants) before clinical manifestation
- Typical clinical manifestation
- Myalgia, myositis or muscular weakness
- Arthralgia and / or arthritis
- Chronic fatigue, not rested after sleep or sleep disturbances
- Neurological manifestations (especially associated with demyelinating diseases)
- Cognitive problems, reduced memory
- Typical biopsy from affected organs
Minor
- Autoantibody or Antibodies against suspected adjuvants
- Other clinical manifestations (e.g. Irritable bowel syndrome)
- Specific tissue HLA (Eg HLA DRB1, HLA DQB1)
- Development of autoimmune disease (SLE, Multiple sclerosis, Sjögren's syndrome and others)
ASIA Syndrome, BINDEVEVSSYKDOMMER.no
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