Suggested criteria for the diagnosis: (Either 2 major or 1 major + 2 minor)

Major

• Exposure for external stimulus (infection, vaccine, silicone, adjuvants) before clinical manifestation
• Typical clinical manifestation
  • Myalgia, myositis or muscular weakness
  • Arthralgia and / or arthritis
  • Chronic fatigue, not rested after sleep or sleep disturbances
  • Neurological manifestations (especially associated with demyelinating diseases)
  • Cognitive problems, reduced memory
  • Typical biopsy from affected organs

Minor

• Autoantibody or Antibodies against suspected adjuvants
• Other clinical manifestations (e.g. Irritable bowel syndrome)
• Specific tissue HLA (Eg HLA DRB1, HLA DQB1)
• Development of autoimmune disease (SLE, Multiple sclerosis, Sjögren's syndrome and others)

ASIA Syndrome, BINDEVEVSSYKDOMMER.no