CANDLE syndrome Please rate this page (bottom of page)

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CANDLE syndrome is considered among them periodic fever syndromes / autoinflammatory diseases. Chronic atypical neutrophilic dermatitis with lipodystrophy and elevated temperature (CANDLE) (Autoinflammation, lipodystrophy and dermatosis syndrome, ALDD)


  • Begin early in childhood or infant
  • Daily fever is common, but not always
  • Recurrent, troublesome sores on the skin
  • Weight Loss
  • Hepatomegaly (large liver)
  • Swollen fingers
  • Systemic inflammation (inflammatory reaction) with signs of inflammation in blood samples (SR and CRP)



Auto-inflammatory diseases (

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