Criteria FMF 4/5 (1)

Share Button

These are classification criteria used in research and not necessarily to make the diagnosis in clinical practice.

Classification criteria Eurofever / PRINO 2019 (Gattorno M, 2019)

Genetic testing shows MEFV genotype and at least one of the following:

  • Duration of episode 1-3 days
  • Arthritis (joint inflammation)
  • Chest pain
  • Abdominal pain

OR

Absence of genetic test showing MEFV genotype and at least two of the following:

  • Duration of episode 1-3 days
  • Arthritis (joint inflammation)
  • Chest pain
  • Abdominal pain

Suggested criteria (Federci, S, PRINTO / Eurofever 2015)

Occurrence swath

  • Episodes <2 Day 9
  • Chest pain 13
  • Abnormal pain 9
  • Ethnicity * 22
  • Absence of Oral stomatitis 9
  • Absence of Urticary eczema 15
  • Absence of Enlarged throat nuts 10
  • Absence of Duration of episodes> 6 days 13

TOTAL SCREEN at least 60

* Turkish, Armenian, Jewish, Arabic, Italian, Spanish, Greek

Sensitivity: 68%. Specificity: 87%

Livneh A (1997): Criteria: ≥1 major gives sensitivity to 57%, specificity on 99%:

  • Major: Attaks with
  • Minor: Uncompleted attaks:
    • The abdomen (abdominal area)
    • Thorax (breast area)
    • Joints (Arthritis)
    • Bone Pain
    • Colchicine-repons
  • Supportive: Familial occurrence, typical ethnicity, <20's age first episode, episodes require bedtime, spontaneous remission, symptom-free interval. Lab shows inflammation, episodes of ery- / proteinuria, Appendectomy without discovery, Parents of the same family

This page has had 1 visits today

Please rate this page