RoActemra (tocilizumab) Please rate this page (bottom of page)

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This page contains a brief description that does not cover the medication. For more information read the review in Felleskatalogen.no for the respective drug.

Definition

RoActemra is an Biological drug which inhibits the cytokine interleukin-6 (IL-6) in the immune system. RoActemra is given to rheumatic diseases, either as a syringe (subcutaneous, Sc) or injection (intravenously, iv).

Before start of treatment

Dosage

  • Adults (usually)
    • Subcutaneous dose 162mg / week
    • iv 8 mg / kg every X. week
  • Children get the dose adjusted to body weight

Prescription

Measurement of serum concentration

  • Tocilizumab, Oslo University Hospital on their own requisition
  • Reference range of tocilizumab in blood sample (bottom concentration just before the next infusion): Please see anx.no (tocilizumab)

Medical checkup / follow-up

  • Infections must be excluded (although CRP is normal)
  • CRP is (almost) always normalized and the sedimantation rate (ESR) lower, but the changes do not always correlate with the treatment response
  • Antibodies are rarely formed

Patient information

Medications, BINDEVEVSSYKDOMMER.no


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