Purpura at low platelet count: User Hector - the English Wikipedia: http://en.wikipedia.org CC BY SA 3.0

Definition

Evans syndrome is Hemolytic anemia + low platelet count (thrombocytopenia), possibly thrombocytopenic purple.

• Evans syndrome may be primary (without associated disease) or secondary by, among other things SLE, Sjøgren`s syndrome, Antifosfolipid syndrome or Hashimoto's thyroiditis.

Disease Cause

Autoimmune disease where antigens attack red blood cells (erythrocytes) and platelets (platelets)

Diagnosis

Blood tests: Detect Hemolytic anemia (high LD, low haptoglobin) and measure low platelet count. Investigate others Autoimmune conditions may be present

Treatment

Corticosteroids, immunoglobulin (IVIG), rarely require additional immunosuppressive treatment (including rituximab).

Literature

• Barcellini W, 2015

• Bindevevssykdommer.no
• Vaskulitt.no