
Purple at low platelet count: User Hektor - the English Wikipedia: http://en.wikipedia.org CC BY SA 3.0
Definition
Evans syndrome is Hemolytic anemia + low platelet count (thrombocytopenia), possibly thrombocytopenic purple.
- Evans syndrome can be primary (without associated disease) or secondary to, among other things SLE, Sjøgren`s syndrome, Antifosfolipid syndrome or Hashimoto's thyroiditis.
Disease Cause
Autoimmune disease where antigens attack red blood cells (erythrocytes) and platelets (platelets)
Diagnosis
Blood tests: Detect Hemolytic anemia (high LD, low haptoglobin) and measure low platelet count. Investigate others Autoimmune conditions may be present
Treatment
Corticosteroids, immunoglobulin (IVIG), rarely require additional immunosuppressive treatment (including rituximab).