Contents
Definition
Fatigue is morbid fatigue and prolonged or recurrent fatigue with reduced capacity for mental and / or physical activity (reference: Krupp LB, 1996). Fatigue can be divided into subgroups such as: "general fatigue", "physical fatigue", "mental fatigue" and "mental fatigue".
Chronic fatigue is observed in a variety of diseases and conditions, including Systemic connective tissue diseases: and other rheumatic diseases.
From the animal kingdom, we recognize symptoms of fatigue in infectious diseases. Animals hide to rest until their physical condition improves ("sickness behavior", reference: Heart BL, 1988). That way, they protect themselves from attack by predators in an exposed phase.
Conditions with fatigue
- Connective Tissue Diseases
- Mentally
- Nutritional Deficiency
- Drug Addiction
- Medication
- Sleep medicine and sedative medication
- Blood pressure medication (beta blocker)
- Antidepressants
- Fabry's disease (hereditary enzyme deficiency)
- Hormonally
- hypothyroidism (TSH, F-T4)
- hyperthyroidism (TSH, F-T4)
- Diabetes mellitus (Blood sugar, HbA1c)
- Pituitary failure (ACTH, FSH, LH, TSH, growth hormone, prolactin)
- Hyperparathyroidism (calcium, PTH)
- Adrenal crisis (Addison's disease; low cortisol level, high ACTH, non-measurable aldosterone level and elevated plasma renin concentration or renin activity (PRA))
- Hypercalcemia (Ca, ionized Ca, PTH, 25OH-White D)
- Chronic renal failure (Creatinine, GFR, urine)
- Liver failure (Liver enzymes, albumin)
- Cancer
- After a stroke or brain damage
- Low hemoglobin (serious anemia: Hgb, haptoglobin, MCV, transferrin receptor, vitamin B12, folic acid)
- Infections
- Endocarditis (Blood cultures)
- Tbc (IGRA tests)
- Mononucleosis (EBV) (Blood test)
- Hepatitis (Hepatitis B og C tests)
- Parasitic disease (eosinophilic leukocytes, various)
- HIV Infection (HIV test, CD4 T cells)
- Cytomegalovirus virus (CMV-PCR from blood, urine and other)
- Chronic heart failure (Pro-BNP)
- COPD (C examination of lungs)
- Sleep apnea (ENT, Sleep Laboratory)
- Oesophageal reflux (gastroscopy, x-ray of the esophagus)
- Allergic rhinitis (Allergy study)
- Unknown cause (exclusion diagnoses)
- Idiopathic Chronic Fatigue (unknown cause)
- Chronic fatigue syndrome, ME, CFS
- Fibromyalgia
Incorrect diagnosis (Similar conditions / Differential diagnoses)
-
Narcolepsy
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Sleep apnea
- Night sleep with abnormal breathing breaks causes a pronounced fatigue a day. Children can develop hyperactivity
Measurement / registration of fatigue
Literature
- More about fatigue / fatigue (after brain injury and brain stroke) (Norwegian doctor's association)
- Chronic fatigue syndrome, ME, CFS: (Bindevevssykdommer.no) here
- Wikipedia (English)
- Lupus and fatigue (Yuen HK, 2014)