Jessner's disease (cutaneous lymphoid hyperplasia)
Contents
Definition
Jessner's disease is a skin disease with persistent nodules (papules) and plaque most often on the neck, back and face. Benign accumulations of lymphocytes. Most people who are attacked are under the age of 50, both men and women. It is a rare condition of unknown cause that was described as 1953 by Jessner and Kanof (Jessner-Kanof lymphocyte infiltrate).
- Possibly the disease Lupus erythematosus tumidus also the same condition
- Jessner's disease is not one systemic connective tissue diseasebut the symptoms may look like, especially on SLE with discoid lupus in the skin
Symptoms
Painless knot or plaque on the neck, face or back. One or more lesions. Some are triggered by sun. Duration for several months to year. Lesions on 2mm-2cm, sometimes with central clarification.
Diagnosis
Tissue sample (biopsy): lymphocyte infiltration
Incorrect diagnosis? (Similar diseases / differential diagnoses)
- Mycosis fungoides
- Lyme disease
- Granuloma annulare
- Granuloma facial
- Diskoid lupus erythematosus (Skin lupus)
- Lupus erytematosus tumidus may be part of the same disease (is under discussion)
- Histological (biopsy), Lupus erythematosus tumidus (and reticular erythematous mucinosis) should have marked mucin deposition in the skin
- Leprosy
Treatment
Most often, one waits for the disease to return spontaneously. Cosmetic treatment. Alternatives are surgery, laser or, in some cases, trials with immunosuppressive drugs
Course
Spontaneous decline after months-years
