Contents
Diagnosis is based on
- Disease history
- Clinical examination
- RNP antibody (required!)
- Exclude other cause of illness (Differential diagnosis)
Medical examinations
Disease history
- Time and symptoms of disease start (Raynaud's phenomenon and non-Raynaud's symptoms)
- Time of diagnosis
- "Puffy Hands" (Early finding)
- Raynaud's phenomenon (in most cases)
- Arthritis (rarely erosive, often in small joints)
- Myositis (Often low grade with slightly elevated CK and few symptoms)
- Sclerodactylia (transition towards Systemic sclerosis)
- Fatigue / exhaustion
- Eczema (note! SLE)
- Kidney Disorders (Obs! SLE)
- Heart / lungs (note! SLE)
- Fever (Obs! SLE)
- Cytopenia (obs! SLE)
- RNP antibody
Clinical examination
By clinical investigation, special consideration is given:
- Swollen fingers (puffy hands)?
- Arthritis
- Jaccouds arthropathy or destructive arthritis
- Myositissign
- Muscle atrophy
- Reduced force (symmetrical, proximal or distal, rises from the hernia and from the chair without support?
- High CK and LD in blood
- Sclerodactylia?
- Eczema (SLE-like)
- Kidney
- Glomerulonephritis: differential diagnosis SLE
- Lungs
- Pleurisy
- Heart Disorders
- Pericarditis (rare)
- Pulmonary hypertension (rare)
Blood tests
- Antibodies (RNP is mandatory)
- Sedimentation rate (ESR) and CRP, cell counts, liver enzymes, renal function, f-T4 and TSH
Urin test
- Exclude proteins and blood (by glomerulonephritis)
Capillaroscopy
- Capillary neoangiogense, megacapillaries (not all)
CT lungs (frosted glass, fibrosis)
ECG
Ekkocardiografi
Norwegian Directorate of Health (Supervisor for referrals)
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