Ebola and rheumatic disease Please rate this page (bottom of page)

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Definition

Virus infection caused by Ebola virus. Serious disease course. Rheumatic symptoms can be part of the disease picture.

Contamination

Epidemics in West Africa. Transfer between people via direct contact, blood or other body fluids.

Symptoms

  • Flu-like (but usually not sore throat or chest pain)
    • Exhaustion
    • Fever
    • Headache
    • Arthralgia and muscle pain
    • Abdominal pain
  • Quick start
  • Vomiting and diarrhea
  • Some people get rash
  • The plagues usually occur 8-10 days after infection (incubation period)
  • Bleeding from the mucous membranes (gastrointestinal, nose, gums, vagina) occurs after 5-7 days from symptom depletion at 40-50%
  • Bleeding is a serious symptom that worsens the prognosis

Rheumatic symptoms

  • Joint pain and muscle pain in the acute disease phase and as a chronic manifestation (reference: Amissah-Arthur MB, 2018)

Diagnosis

Travel history. Antibody tests (ELISA) and PCR most applicable. Virus detection also possible, but takes longer. Electron microscopy can recognize viruses but not specific types.

Treatment

The treatment is to provide fluid, analgesic and fever-reducing treatment in the isolation / intensive care unit (in western countries).

Vaccine

  • An ebola vaccine has been developed

Prognosis

If recovery does not occur, multiorganic failure occur and death follows. Weakened persons (high age, HIV, other illness) are most vulnerable. Mortality is more than 50%.

Differential diagnosis

Literature

Tropic diseases, BINDEVEVSSYKDOMMER.no


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