Listeriosis and rheumatic disease Please rate this page (bottom of page)

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Definition

Listeriosis (listeria monocytogenes) is a bacterial infection that occurs after ingestion of infected foods (raw meat, fruits, vegetables, seafood, dairy products). Infection during pregnancy can cause infection in the newborn or stillbirth.

  • In a weak immune system that may be present in immunosuppressive therapy in rheumatic diseases, listeria can give muscle aches, joint infection (Septic arthritis) and meningitis (meningitis).

Symptoms

After gastro-intestinal infection (gastroenteritis) during food poisoning, the symptoms averaged 24 hours later (latency)

  • Fever
  • Diarrhea and vomiting
  • Dizziness
  • Arthralgia and muscle pain
  • Duration of up to 2 day course with full refresh

Meningitis / meningoencephalitis (via bacteria in the blood):

  • Influenza-like start
  • CNS (Brain)
    • Headache
    • Neck stiffness
    • Ataxia, tremor, hemiplegia, deafness
    • Disorientation
    • Changed mental status
    • Convulsions

Pregnancy (XNUMBER):

  • Flu like symptoms
  • Fetal death, premature birth
  • Infected newborns (life threatening)

Diagnosis

Can only be made by growing bacteria from blood and cerebrospinal fluid

  • Lumbar puncture
    • Cerebrospinal fluid with moderately increased protein, low glucose, lymphocytes more than 25%. Gram staining positive in just one of three cases
    • MRI examination of the brain should be taken with contrast agent

Treatment

Ampicillin + gentamycin.

  • Meningitis is usually treated over 3 weeks, brain abscess is treated in 6 weeks

Literature

Opportunistic infections, BINDEVEVSSYKDOMMER.no


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