
Eczema by Parvovirus B19 that triggered Marophagic Activation Syndrome (MAS). Soldo-Juresa D, 2015. CC BY 2.0
Contents
Definition
Parvovirus B19 does not cause a classic ”Opportunistic infection"but important to consider among people who get immunosuppression. Parvovirus B19 Causes Rash (erythema infektiosum), The so-called 5. childhood disease among young children.
- In addition, infection can cause significant Joint pain (arthralgia)
Symptoms
Debut
- Flu-like symptoms
- Fever
- Tiredness
- Headache
- Muscle pain (myalgia)
- Cold
- Itching
- Blood: Low blood cells: anemia, leukopenia, thrombocytopenia
The following week
- Rash (rubella-like, less typical in adults than in children (erytehma infectiosum)
- Joint pain (arthralgia)
- Among children with Erythema infectiosum, about 10% gets joint pain which can also be the only symptom of the infection
- Adults can get one arthritis-like (RA) prevalence with pain and swelling in many joints, including finger joints.
- The joint pain returns by itself within three weeks, less often after a few months.
Associations and Complications
- The 5. childhood disease (erythema infectiosum)
- Joint pain and arthritis
- Infection in pregnancy:
- Non-immune hydrops fetalis Intrauterine fetal death or spontaneous failure
- Transient aplastic crisis (too low blood cell count) in chronic haemolytic disease
- Chronic low hemoglobin in immunosuppressed patients
- Red and painful hands and feet
- Blisters and later flaking of skin occur
- Duration 1XX weeks
- Myocarditis and dilated cardiomyopathy
- Macrophage activation syndrome (MAS) / HLH
Literature
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