1) By Muhammad Mahdi Karim (www.micro2macro.net) Facebook Youtube - Own work, GFDL 1.2, https://commons.wikimedia.org/w/index.php?curid=11185617 2) By Beth.herlin - Own work , CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=46867814

Zika virus infection

Definition

Viral infection transmitted to humans via mosquito bites, mainly via Aedes Mosquito. Can probably also be infected through sexual contact and through blood transfer.

• One must expect that people with a weakened immune system, such as immunosuppressive treatment for rheumatic diseases, may have a more serious course of disease
• Joint pain og muscle aches part of the disease picture

Proliferation of Zika virus

Africa, Asia and Latin America (major outbreak in Brazil)

Symptoms

• Fever
• Exhaustion
• Rash
• Conjunctivitis

Rheumatic symptoms

• Joint pain
• Muscle pain

Pregnancy and Zika virus

• There is an increased risk of fetal injury (mikrocephali) if a pregnant is infected, especially in the led 1 / 3 of pregnancy
• A study of 442 infected pregnant women showed that 6% gave birth to children with injuries following Zikavirus infection (reference: Honein MA, 2017)
  • Everyone with injured children was infected during the first three months of pregnancy
  • The risk of fetal injury is independent of whether the pregnant woman has symptoms of infection or is infected without noticeable symptoms
• Fetal injuries include brain damage, microcephaly (small head) and fetal death (reference: Brasil P, 2016)
• Concomitant zika syndrome can be defined (reference: Hoen B, 2018)
  • Serious microcephaly
  • Special brain formation
  • Changes in the eye (retina)
  • Joint malformations (like lumps)
  • Spasticity
• Due to the epidemic from 2016, the health authorities of several South American countries have asked women to postpone pregnancy to 2018 or later

Literature

• Ploured AR, 2016 (Zicka virus)
• The Norwegian Public Health Institute
• Brasil P, 2016

• Bindevevssykdommer.no
• Vaskulitt.no