When is a rheumatic disease in "remission"?
By remission is meant that the disease calms down, without measurable disease activity. Remission is thus distinguished from low disease activity. Although remission of rheumatic disease is not the same as cure, it is a desirable goal of treatment (treat to target, T2T) of which connective tissue disorders og vasculitides that Systemic lupus (SLE), GPA / Wegeners granulomatosis, Rheumatoid arthritis (RA / arthritis).
There are several ways to define remission:
- It implies the absence of typical disease manifestations over time. This means that the disease has gone into hibernation, without symptoms.
- "Serological remission" is defined as the absence of typical "Tear samples" / serological markers and / or absence of low complement factors (most applicable to SLE og Sjögren's syndrome).
- One differ remission without drugs from equivalent on medications. Remission of medications allows the use of hydroxyclorokine (Plaquenil) in Systemic lupus (SLE), a low dose prednisolone (eg 5 mg / day or less) and NSAID (ibuprofen, naproxen, diclofenac and more) in the chronic diseases the drug is relevant.
- In ANCA vasculitis (GPA / Wegeners granulomatosis, MPA / Microscopic polyangiite / EGPA / Churg-Strauss vasculitis) are used frequently BVAS score = 0 as a remission
- Rheumatoid arthritis (RA / arthritis) is used Boolean based definition or DAS28 score less than 2,6 as criteria for remission