When is a rheumatic disease in "remission"?
Definition of remission
By remission is meant that the disease calms down, without measurable disease activity. Remission of rheumatic disease such as connective tissue disorders og vasculitides is the desired goal of treatment (treat to target, T2T) of Systemic lupus (SLE), GPA / Wegeners granulomatosis, Rheumatoid arthritis (RA / arthritis), with more.
There are several ways to define remission
- Remission involves absence of typical disease manifestations over time
- Remission means that the disease has entered hibernation, without symptoms
- "Serological remission" is defined as the absence of typical "Tear samples" / serological markers and / or absence of low complement factors (most applicable to SLE og Sjögren's syndrome)
- One differ remission without drugs from remission on drugs
- Remission is not the same as that the disease is cured
- Remission is distinguished from low disease activity
- In ANCA vasculitis (GPA / Wegeners granulomatosis, MPA / Microscopic polyangiite / EGPA / Churg-Strauss vasculitis) are used frequently BVAS score = 0 as a remission
- Rheumatoid arthritis (RA / arthritis) is used Boolean based definition or DAS28 score less than 2,6 as criteria for remission