Definition

A doctor who has experience with Sjøgren's syndrome will usually make the correct diagnosis without uncertainty. However, in special cases, the diagnosis may be difficult. The proposals for differential diagnoses (similar conditions) below can then be considered.

Overlapping symptoms with Sjøgren's syndrome

Other connective tissue disorders

• Rheumatoid arthritis with "secondary Sjögren's syndrome"
• SLE
• Systemic sclerosis
• By abnormalities in ANA and SSA
  • SLE
  • Myositis

Paraneoplastic syndrome (in cancer)

• Graft versus Host disease (GVHD, rejection reaction)

Dry and painful eyes

• Vitamin A deficiency
• Chronic blepharitis or conjunctivitis
• Roseacea
  • Ocular roseacea causes irritation and dryness in the eyes
• Reduced blinking
  • After trauma (injury)
  • Parkinson's disease
  • Facial paresis ("Bell's paralysis" in facial muscle)
  • Aging (reduced blink reflex)
• Work on PC monitor
• Infiltrations in lacrimal glands
  • Amyloidosis
  • Sarcoidosis
  • Lymphoma
  • IgG4-related disease
• Low estrogen levels
  • Postmenopause
• Medications with anticholinergic effect
  • Parkinson medication
• Herpes simplex or zoster
• Cornea (cornea) injury to the eye
• Previous corneal intervention

Dry mouth

• Medications with anticholinergic effect
  • Antidepressants
  • Antihistamines
  • Beta-blockers
  • Some antiepileptics
• Sialo-adenitis at salivary gland stones
• Alzheimer's disease
  • Autonomic neuropathy
• Multiple Sclerosis (MS)
  • Demyelinating process

Swollen parotid glands and dryness

• Salivary gland stone
• Infection
• Heerford syndrome
• Parotitis
• Uveitis
• Fever
• Lymphoma
• Infections
  • Hepatitis C
  • HIV (Diffuse Infiltrative Lymphocytosis Syndrome / DILS, with swollen salivary glands / Parotitis)
• Kimura (most often in Asia)

Bacterial infection in salivary gland

• Most often after obstruction in exit duct
• Unilateral (one page)
• Pain
• Fever
• Pain in the gland
• Tbc
• Actinomycosis

Virus Infections

• Coxakie
• Echo virus
• Epstein-Barr virus
• Hepatitis C
• HIV
• Mumps

Tumors (cancer)

• Adenoma
• carcinoma
• Lymphoma
• Mixed types

Benign tumor (benign tumor):

IgG4 disease

• Kutter's tumor / sclerosing sialoadenite / Mikulicz / IgG4 disease

• • • Mikulicz'

Radiotherapy

• Against cancer in the head / throat areas

Sarcoidosis

Eating Disorders / Anorexia

• Malnutrition
• May cause significant swelling of salivary glands

Alcoholism

Acromegaly

Diabetes mellitus (diabetes)

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• Sjögren's Syndrome, BINDEVEVSSYKDOMMER.no
• Bindevevssykdommer.no
• Vaskulitt.no

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