The heart in SLE 1/5 (3)

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  • Heart attacks Lupus in up to 50% of cases (autopsy)
  • Mostly mild, with no symptoms or need for treatment
  • Clinical symptoms are seen in approximately one in four
  • Pericard (pericarditis) seen at 11-55%
    • Symptoms of Pericarditis are chest pain that is enhanced when lying flat and improved when sitting or standing
  • Myocardium is a heart muscle that can become inflamed (myocarditis) Of 10-15%
    • Symptoms of heart failure, troponin and creatine kinase (CK) are elevated in blood tests
  • Libmann-Sacks endocarditis
    • Endocardium (inner part of the heart and heart valves (mitral valves most commonly) are attacked at 10-30%,
      • Diagnosis
        • ECG
        • Echocardiography: Trans-thoracic 10%, Trans-oesophageal 30%
        • MRI
      • Enzymes are normal
  • Pulmonary hypertension
    • Symptoms of heart failure
  • Coronary artery disease (coronary arteries) by atherosclerosis


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