Tubulo-interstitial nephritis and uveitis (TINU) syndrome 5/5 (1)

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Uveitis and kidney inflammation at the TINU syndrome. Barut K, 2015. CC BY 4.0

Definition

Tubulo-interstitial nephritis and uveitis syndrome (TINU syndrome) is an Autoimmune disease that attacks eyes (uveitis) and kidneys (Tubulo-interstitial nephritis, TIN). The condition was first described 1975 and is rare.

Symptoms of TINU

Investigational Findings

  • Blood tests with
  • Urine
    • A little protein
    • Erythrocytes
  • Renal Biopsy (Tissue Test)
    • Typical tubulo-interstitial nephritis

Treatment

  • Cortisone
  • Suppressive supplemental treatment when needed

Prognosis

Kidney failure goes back to 64%, while kidney transplantation is currently in 13% over time. The prognosis depends on early diagnosis and the individual response to treatment (reference: Baker RS, 2004)

Literature



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